microRNA target identification by transcriptomics

miRNAtarget 2.0

(Release date: 2022-04-06)

miRNAtarget is a software tool under continuous development for the analysis of the targets of differentially expressed miRNAs.

To perform miRNA-target analyses please signup. Up to twenty (20) miRNAtarget analyses is free of charge for research use. For more than twenty (20) miRNAtarget analyses for research use and for commercial use please inquire about pricing at businessdevelopment @pharmahungary.com.

Papers published so far on the utilization and validation of the miRNAtarget software

Our team published several scientific papers on the utilization and experimental validation of the predictions assessed by the miRNAtarget software. The 3 most recent publications on miRNAtarget:

  1. Heger J, Partsch S, Harjung C, Varga ZV, Baranyai T, Weiß J, Kremer L, Locquet F, Leszek P, Ágg B, Benczik B, Ferdinandy P, Schulz R, Euler G.
    YB-1 Is a Novel Target for the Inhibition of α-Adrenergic-Induced Hypertrophy.
    Int J Mol Sci. 2023 Dec 28;25(1):401.
  2. Ruppert M, Korkmaz-Icöz S, Benczik B, Ágg B, Nagy D, Bálint T, Sayour AA, Oláh A, Barta BA, Benke K, Ferdinandy P, Karck M, Merkely B,
    Radovits T, Szabó G.
    Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats.
    Sci Rep. 2023 Sep 26;13(1):16122.
  3. Aczél T, Benczik B, Ágg B, Körtési T, Urbán P, Bauer W, Gyenesei A, Tuka B, Tajti J, Ferdinandy P, Vécsei L, Bölcskei K, Kun J, Helyes Z.
    Disease- and headache-specific microRNA signatures and their predicted mRNA targets in peripheral blood mononuclear cells in migraineurs: role of inflammatory signalling and oxidative stress.
    J Headache Pain. 2022 Sep 2;23(1):113.

Complete list of research articles on miRNAtarget ...

Developed by

miRNAtarget was developed in the collaboration of the Pharmahungary Group and the Department of Pharmacology and Pharmacotherapy, Semmelweis University.

Supported by

This study was supported by the National Research, Development and Innovation Office of Hungary (NKFIA; National Heart Program NVKP-16-1-2016-0017). The research was financed by the Thematic Excellence Programme (2020-4.1.1.-TKP2020) of the Ministry for Innovation and Technology in Hungary, within the framework of the Therapeutic Development and Bioimaging thematic programmes of the Semmelweis University. Project no. RRF-2.3.1-21-2022-00003 has been implemented with the support provided by the European Union.

Contact

If you need technical support please contact
[email protected].

Terms and Conditions

Please read Terms and Conditions of the miRNAtarget service.

miRNAtarget 2.0 features

(release date: 2022-04-06)

Aims

  • to analyze the targets of miRNAs from a network theoretical perspective
  • to predict the most probable targets of differentially expressed miRNAs

Advantages

  • miRNAtarget relies on multiple miRNA-target interaction databases
  • simple and powerful network theoretical approach to identify the most probable targets of differentially expressed miRNAs
  • increased coverage of possible miRNA-target interactions compared to experimentally validated databases
  • higher accuracy than available predicted miRNA-target interaction databases
  • intuitive relative entropy optimization-based network visualization
  • interactions predicted by miRNAtarget has been successfully validated in multiple animal studies

Recommended for

  • basic researchers
  • small biotech companies
  • pharmaceutical industry
This study was supported by the National Research, Development and Innovation Office of Hungary (NKFIA; National Heart Program NVKP-16-1-2016-0017). The research was financed by the Thematic Excellence Programme (2020-4.1.1.-TKP2020) of the Ministry for Innovation and Technology in Hungary, within the framework of the Therapeutic Development and Bioimaging thematic programmes of the Semmelweis University. Project no. RRF-2.3.1-21-2022-00003 has been implemented with the support provided by the European Union.